The HARPER Lab

Department of Cell Biology
  • Maps of unstudied open reading frames from the BioPlex interactome study
  • Mitochondria EM
    EM analysis of purified mitochondria
  • Parkin translocation to mitochondria
    CCCP-dependent loading of PARKIN on mitochondria
  • Parkin Activation by Phosphorylation
  • Poly Nature

News

Sep 2020

Check out out paper with Rachel Green identifying EDF1 as a key regulator of ribosome collisions - great application fo TMT proteomics to discovery new proteins in polysomes (EDF1). https://elifesciences.org/articles/58828

Sep 2020

Congratulations to our neighbors in the Shao lab for the great collaboration with Alban in the lab on the identiifcation of ATP13A1 as a transmembrane dislocase that removes mislocalized tail-anchored proteins from the ER. Such mis-localized proteins include those that normally are localized to mitochondria. Thanks for the great collaboration! https://pubmed.ncbi.nlm.nih.gov/32973005/

Sep 2020

Very happy to announce that Kelsey Hickey and Felix Kraus have joined the lab. Kelsey was a graduate student in Jonathan Weissman's lab at UCSF and worked on ribosomal quality control (RQC), including a recent paper in Mol Cell. Felix was a graduate student in Mike Ryan's lab in Melbourne and worked on Dynamin and mitochondrial fission/fusion dynamics. Welsome to both!!

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